Predicted Secretome of the Monogenean Parasite Rhabdosynochus viridisi: Hypothetical Molecular Mechanisms for Host-Parasite Interactions
نویسندگان
چکیده
Helminth parasites secrete several types of biomolecules to ensure their entry and survival in hosts. The proteins secreted the extracellular environment participate pathogenesis anthelmintic immune responses. aim this work was identify functionally annotate excretory/secretory (ES) monogenean ectoparasite Rhabdosynochus viridisi through bioinformatic approaches. A total 1655 putative ES were identified, 513 (31%) annotated UniProtKB/Swiss-Prot database, 269 (16%) mapped 212 known protein domains 710 GO terms. We identified six multifunctional proteins. 556 179 KEGG pathways 136 KO. ECPred predicted 223 enzymes (13.5%) 1315 non-enzyme (79.5%) from secretome R. viridisi. 1045 (63%) as antigen with a threshold 0.5. also venom allergen-like Our results suggest that are involved evasion strategies some may contribute immunogenicity.
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ژورنال
عنوان ژورنال: Parasitologia
سال: 2023
ISSN: ['2673-6772']
DOI: https://doi.org/10.3390/parasitologia3010004